Patients from lower socioeconomic status (SES) backgrounds are more likely to undergo temporal artery biopsy (TAB) but are not at increased risk for biopsy-confirmed giant cell arteritis (GCA), ...

A late-stage trial testing Novartis’ Cosentyx in individuals with giant cell arteritis failed to meet its primary endpoint. The phase 3 study tested Cosentyx alongside a 26-week steroid taper and ...

Novartis NVS announced that a late-stage study of its interleukin-17A inhibitor, Cosentyx (secukinumab), has failed to meet ...

A total of 93 patients received temporal artery biopsy (TAB), among which 53 (57%) had positive results; 18 out of 63 patients (27.3%) yielded positive results on color Doppler ultrasounds of the ...

Patients with predominantly cranial vs isolated extracranial GCA phenotypes present with different patterns of arterial involvement on 18F-FDG PET-CT scans.

Background The Prognostic Nutritional Index (PNI), calculated from serum albumin levels and lymphocyte counts, is a simple ...

Background: A number of centres are now running fast track pathways for diagnosis and management of Giant cell arteritis with ultrasound as the first port of call for diagnosis1. Temporal artery ...

The objective was to provide a clinical setup for photoacoustic imaging (PAI) of the temporal artery in humans and to describe the challenges encountered and methods of overcoming them. The temporal ...

Background Vascular inflammation persists in temporal artery biopsy (TAB) of giant cell arteritis (GCA) patients even after prolonged glucocorticoid (GC) therapy. We aimed to evaluate the histological ...

Objective To identify differentially expressed genes in temporal artery biopsies (TABs) from patients with giant cell arteritis (GCA) with different histological patterns of inflammation: transmural ...

Temporal artery ultrasound may effectively serve as a first-line diagnostic tool for giant cell arteritis, potentially replacing the need for invasive biopsies among patients with high clinical ...