Researchers at Martin Luther University Halle-Wittenberg (MLU) have developed a promising new substance for targeting ...

Researchers at Martin Luther University Halle-Wittenberg (MLU) have developed a promising new substance for targeting bacteria that cause tuberculosis. The team have produced a compound that inhibits ...

The chemical ATP, adenosine triphosphate, is the fuel that powers all life. Despite ATP's central role, the structure of the enzyme generating ATP, F1Fo-ATP synthase, in mammals, including humans, has ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Nimbus Therapeutics, a biotechnology company applying deep computational expertise throughout drug discovery and development, today published research in Nature ...

By designing a squaric acid amide that binds a new site on ATP synthase, researchers created PRP020, a potential therapy for ...

DNA aptamers are powerful molecular tools in biosensing, bioimaging and therapeutics. However, a limited understanding of their tertiary structures and binding mechanisms hinders their further ...

The link between p38 mitogen-activated protein (MAP) kinase (p38) and many diseases has led to an avalanche of research dedicated to finding inhibitors of this signal-transduction molecule. In Nature ...

ATP is the main source of energy for most cellular processes. The building blocks of ATP are carbon, nitrogen, hydrogen, oxygen, and phosphorus. Because of the presence of unstable, high-energy bonds ...

iCeMS scientists have revealed how a transporter protein twists and squeezes compounds out of cells, including chemotherapy drugs from some cancer cells In 1986, cellular biochemist Kazumitsu Ueda, ...