Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated KRAS G12C (N Engl J Med 2023;389:2125-2139). As a result of late data entry, a reanalysis using a later data snapshot (March ...

The New England Journal of Medicine (NEJM) employs a media embargo system, which allows journalists time to conduct interviews in the days before an article’s publication. Qualified journalists ...

The CMS Innovation Center is approaching the next negotiation cycle for the CGT Access Model. Several considerations will guide the selection of future candidate diseases and potential new model ...

Faced with a young woman whose seizures, of untraceable cause, can’t be stopped by the medical team, a medical student viscerally learns the limits to what can be accomplished by pushing harder.

Explore this issue of The New England Journal of Medicine (Vol. 389 No. 20).

The nonsteroidal mineralocorticoid receptor antagonist finerenone has been reported to improve kidney and cardiovascular outcomes in persons with type 2 diabetes and chronic kidney disease (CKD).

Supported by grants from the Deutsche Forschungsgemeinschaft, a grant (80735240) from the Deutsche Krebshilfe, the Else Kröner Fresenius Stiftung, the Else Kröner Clinician Scientist Program Munich: ...

Type 1 diabetes is characterized by an absolute insulin deficiency and immune dysregulation. Nearly one in three persons with type 1 diabetes will go on to have diabetic kidney disease, 1 an ...

New AI-based software for generating patient notes purposely filters out social “chitchat,” but a primary care physician sees serious risks in that practice, for doctors and patients alike.

The AHEAD model was intended to slow health care cost growth, improve population health, and advance health equity. But under the new administration, its focus has shifted from equity to efficiency.

Private equity firms have gained increasing control of U.S. health care infrastructure. Along with other potential consequences, this growth threatens to undermine progress in health equity.