Patients from lower socioeconomic status (SES) backgrounds are more likely to undergo temporal artery biopsy (TAB) but are not at increased risk for biopsy-confirmed giant cell arteritis (GCA), ...

Small artery disease of the foot typically affects the small, unnamed metatarsal and digital branches and is a pattern found particularly in patients with diabetes and end-stage kidney disease. 19 It ...

Aim: To establish the histological and immunohistochemical parameters that are helpful in recognising temporal arteritis in patients who have been treated with steroids before biopsy, and to analyse ...

A late-stage trial testing Novartis’ Cosentyx in individuals with giant cell arteritis failed to meet its primary endpoint. The phase 3 study tested Cosentyx alongside a 26-week steroid taper and ...

Novartis NVS announced that a late-stage study of its interleukin-17A inhibitor, Cosentyx (secukinumab), has failed to meet ...

Temporal artery biopsy remains the gold standard for diagnosing GCA. Patients require an individualized steroid tapering schedule to minimize side effects.

So consider temporal artery ultrasounds if these are available, the inflammatory markers, temporal artery biopsy, and in select patients consider CTN PET CT and think early about steroid sparing ...

5. Positive temporal artery biopsy Biopsy specimen with the artery showing vasculitis characterized by prominence of mononuclear cell infiltration or granulocyte inflammation, often with ...