Photodynamic therapy (PDT), characterized by its non-invasive nature and precise spatiotemporal selectivity, has garnered considerable attention for its applications in tumor and anti-infection ...

image: Synthesizing hybrid enzyme catalysts in situ to improve and expand enzymatic catalysis is an important way to address challenges of industrial biocatalysis. In this account, the construction ...

Enzymes accelerate reactions by helping to lower the activation energy needed to start them. But how enzymes achieve this has been the subject of intense debate. A research team from Texas and China ...

Figure 1: Hydrolsysis of the acyl–enzyme intermediate formed between β-casomorphin-7 (YPFVEPI) and porcine pancreatic elastase. Here, we describe high resolution crystal structures for cryogenically ...

In a publication selected as a "2007 Hot Article" by the journal Biochemistry, UB chemists report the discovery of a central mechanism responsible for the action of the powerful biological catalysts ...

My laboratory is interested in novel mechanisms of enzyme catalysis, enzyme regulation and designing self-assembling proteins. Our current research projects focus on enzymes that catalyze ...

In living cells, enzymes drive biochemical metabolic processes. It is this very ability which allows them to be used as catalysts in biotechnology, for example to create chemical products such as ...

Reactions that can combine more than two molecular pieces in one go are a powerful way to build complexity quickly and save on costly isolation and purification. But the choreography for such a ...

Scientists achieve a novel biocatalytic reaction by repurposing natural enzymes with light, which could lead to valuable new chemical compounds. Engineering enzymes to perform reactions not found in ...