In vivo and vitro experiments show that long noncoding RNA treatment alleviates pathological cardiac hypertrophy
In a recent study, the regulatory role of the long noncoding RNA (lncRNA) Gm20257 in pathological cardiac hypertrophy has ...
EurekAlert!11d
Berry-flavored may be more dangerous than non-flavored vapes: study
Berry-flavored vapes can weaken the lungs’ natural defenses, making it harder for the body to fight off infections, new ...
News Medical on MSN9d
Moderate expression of CD39 in GPC3-CAR-T cells shows high efficacy against hepatocellular carcinoma
In the quest to enhance the efficacy of chimeric antigen receptor T (CAR-T) cell therapy against hepatocellular carcinoma ...
Simulations Plus and the University of Connecticut Receive New FDA Grant to Expand Mechanistic Modeling Approaches for Long-Acting Injectables
Simulations Plus, in partnership with the University of Connecticut, was awarded a new FDA grant to investigate additional ...
GEN3d
Exercise Causes Muscles to Release Myokines, Speeding Neuron Growth
The team’s in vitro, cell-based experiments found that in the presence of these muscle ... by leveraging established tools for in vivo biochemical stimulation and mechanotherapy, we hope our in vitro ...
DutchNews.NL15d
Simulations Plus and Partners Awarded New FDA Grant to Validate In Vitro-In Vivo Extrapolation Methods for Complex Formulations
Collaboration goal to develop alternative methods to assess clinical performance of product variants under different ...
News Medical on MSN9d
A novel synthetic lethal target for ATM inhibitors in pancreatic cancer
A novel discovery in the field of pancreatic cancer treatment has been unveiled, revealing the epigenetic silencing of BEND4 ...
Frontiers11m
Advancements in Translational Models: Bridging Basic Infection Research and Clinical Applications
Infection research stands at the forefront of global health initiatives, particularly considering emerging pathogens and antimicrobial resistance. The quest for effective interventions necessitates ...