Upadacitinib 15 mg — but not 7.5 mg — alongside a glucocorticoid taper demonstrated superior efficacy to placebo with a ...

Granuloma formation within media. CD4 + T cells secrete IFN-γ and TNF-α which together are responsible for recruitment of macrophages. ... Giant cell arteritis (GCA) ...

A common medication already used for autoimmune diseases such as rheumatoid arthritis is effective for patients with giant ...

“While the phase 3 results of GCAptAIN did not replicate the positive outcomes observed in the phase 2 trial, we remain committed to continuing to drive scientific progress and deepening the ...

Cosentyx missed its main goal in a Phase 3 GCA study, but showed lower steroid use. Novartis plans full review of the trial ...

The US Food and Drug Administration (FDA) has granted approval for AbbVie’s 15mg Rinvoq (upadacitinib) to treat adults with giant cell arteritis (GCA). The approval follows the recent marketing ...

Causes of Giant Cell Arteritis (Temporal Arteritis):Giant Cell Arteritis is an autoimmune disorder where the immune system mistakenly attacks healthy blood vessels, leading to inflammation. While ...

SHREVEPORT, La. - Giant cell arteritis, also known as temporal arteritis, is a less common condition where people get inflammation of the arteries that go to the head and neck.

Peripheral giant cell granuloma (PGCG) is a benign, reactive oral lesion that predominantly affects the gingival and alveolar mucosa. Clinically, PGCG manifests as a red to purple exophytic mass ...

AbbVie (NYSE: ABBV) today announced the U.S. Food and Drug Administration (FDA) has approved RINVOQ® (upadacitinib), 15 mg, once daily, for the treatment of adults with giant cell arteritis (GCA ...

Patients with giant cell arteritis (GCA) who received upadacitinib with a steroid taper regimen achieved sustained remission, according to results from the phase 3 SELECT-GCA study.

Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are linked conditions that occur in the elderly. GCA is a vasculitis of large- and medium-sized vessels causing critical ischemia.