Granuloma Formation to Neutralize Antigen Mature and activated DCs present antigen to CD4 + T cells in the adventitia, leading to T-cell activation and proliferation. These activated T cells ...

Abstract Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are linked conditions that occur in the elderly. GCA is a vasculitis of large- and medium-sized vessels causing critical ischemia.

A common medication already used for autoimmune diseases such as rheumatoid arthritis is effective for patients with giant ...

Cosentyx missed its main goal in a Phase 3 GCA study, but showed lower steroid use. Novartis plans full review of the trial ...

Upadacitinib 15 mg — but not 7.5 mg — alongside a glucocorticoid taper demonstrated superior efficacy to placebo with a ...

“While the phase 3 results of GCAptAIN did not replicate the positive outcomes observed in the phase 2 trial, we remain committed to continuing to drive scientific progress and deepening the ...

A common medication already used for autoimmune diseases such as rheumatoid arthritis is effective for patients with giant ...

Novartis (NVS) stock slips as the company's anti-inflammatory agent Cosentyx fails primary goal in a Phase 3 trial for giant ...

Peripheral Giant Cell Granuloma (PGCG): A lesion that originates from the gingival tissues, often presenting as a reddish nodule, and is generally less aggressive than its central counterpart.

Peripheral giant cell granuloma (PGCG) is a benign, reactive oral lesion that predominantly affects the gingival and alveolar mucosa. Clinically, PGCG manifests as a red to purple exophytic mass ...

Novartis NVS announced that a late-stage study of its interleukin-17A inhibitor, Cosentyx (secukinumab), has failed to meet ...

EXCLUSIVE: Fallen Giant Films, the production company of actor and filmmaker Randy J. Goodwin, on Friday announced a new documentary project exploring the life and legacy of famed soap opera star ...