This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...

Targeted Protein Degradation (TPD) is an emerging drug modality that enables specific degradation of protein targets, offering a powerful approach to tackle previously undruggable targets including ...

Human MAP1LC3B (LC3B) binds proteins involved in autophagy and other cellular processes using a degenerate four-residue short linear motif known as the LC3-interacting region (LIR). Biochemical and ...

Avoid common mistakes in multiplexing protein secretion assays. Discover best practices to ensure accurate results.

Cytokinetics’ heart disease drug secured European approval. Elsewhere, Teva and Sanofi reported longer-term data from an experimental therapy targeting ulcerative colitis and Crohn’s disease.