Recent approvals by the Food and Drug Administration have focused on medications that shrink the sticky brain deposits of a protein called amyloid beta. The errant growth of this protein is ...

Physical examination reveals well-demarcated hyperpigmented macules. Macular amyloidosis is the result of extracellular amyloid deposition within the skin. 1 Severe pruritus is often the presenting ...

Screening for transthyretin cardiac amyloidosis (ATTR‐CA) in patients with severe aortic stenosis (AS) undergoing valve replacement can include screening allcomers vs a more targeted approach.

Hereditary transthyretin (hATTR) amyloidosis is a rare progressive disease that is passed from parent to child. It is caused by a mutant form of the transthyretin (TTR) protein that can damage vital ...

Amyloid-PET (using 18 F-florbetapir) demonstrated moderate widespread amyloid deposition; CSF analysis showed reduced amyloid-beta 1–42 and high-normal total tau. Formal neuropsychological testing ...

CERAD (Consortium to Establish a Registry for Alzheimer’s Disease) is a staging paradigm for Alzheimer’s disease that takes into account amyloid plaque formation 30. Slides were imaged on a confocal ...