The Detroit Lions lost for the first time since Sept. 15 in a high-scoring affair with the Buffalo Bills in Week 15 at Ford Field in Detroit in a matchup of two of the NFL's best teams. The Lions (12-1) fell into an early two-touchdown hole and could not ...

Winning 11 straight games in the NFL — the Detroit Lions’ current streak — is pretty rare. But winning 12 straight, as the Lions could do on Sunday with a victory over the Buffalo Bills at Ford Field (4:25 p.m., CBS)? That’s elite territory ...

The Bills improved to 11-3, two games behind the Kansas City Chiefs in the AFC with three games remaining, and took a one-game lead over Pittsburgh for the conference’s second seed.

Nolan Bianchi, John Niyo, Richard Silva and Bob Wojnowski of The Detroit News offer predictions for Sunday's Lions-Bills game at Ford Field.

The Buffalo Bills (10-3) take on the Detroit Lions (12-1) Sunday in Week 15. Kickoff from Ford Field is set for 4:25 p.m. ET (CBS). Below, we look at Bills vs. Lions odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week.

Kickoff is on Sunday, Dec. 15, at 4:25 p.m. ET on CBS. The Detroit Lions will host the Buffalo Bills at Ford Field for a highly anticipated game.

The second game is the best of the three. The Cincinnati Bengals are a 3-point favorite against the Denver Broncos. The Bengals need to win and then hope to get help to make the playoffs, but they're alive and presumably we'll get their best effort. The Bengals will be a popular side.

The order of the teams that secured their place in the NFL postseason has yet to be defined, but the first favorites in the AFC and NFC are already emerging.

The playoff picture came into sharper focus Wednesday when the Chiefs clinched the AFC’s No. 1 seed and the Ravens leapfrogged the Steelers for the AFC North lead.