The nonsteroidal mineralocorticoid receptor antagonist finerenone has been reported to improve kidney and cardiovascular outcomes in persons with type 2 diabetes and chronic kidney disease (CKD).

As a legacy of African enslavement, structural racism affects both population and individual health in three interrelated domains: redlining and racialized residential segregation, mass incarceration ...

Recent FDA actions related to leucovorin have caused confusion. There is still a lack of scientific evidence establishing that the drug is a safe and effective treatment for autism.

Patients with atrial fibrillation and a moderate-to-high risk of stroke were randomly assigned, in a 1:1:1 ratio, to receive subcutaneous injection of abelacimab (150 mg or 90 mg once monthly) ...

Supported by grants from the Deutsche Forschungsgemeinschaft, a grant (80735240) from the Deutsche Krebshilfe, the Else Kröner Fresenius Stiftung, the Else Kröner Clinician Scientist Program Munich: ...

Explore this issue of The New England Journal of Medicine (Vol. 392 No. 5).

The CMS Innovation Center is approaching the next negotiation cycle for the CGT Access Model. Several considerations will guide the selection of future candidate diseases and potential new model ...

A 54-year-old woman with metastatic breast cancer who was receiving denosumab therapy presented with right jaw pain. An area of exposed, necrotic bone was visualized in the right mandible.

Exactly 20 years ago, the precision-medicine revolution in lung cancer began with the discovery of sensitizing mutations in the epidermal growth factor receptor (EGFR) tyrosine kinase domain,1,2 pr ...

Base editors can correct disease-causing genetic variants. After a neonate had received a diagnosis of severe carbamoyl-phosphate synthetase 1 deficiency, a disease with an estimated 50% mortality in ...

Explore this issue of The New England Journal of Medicine (Vol. 386 No. 1).

Type 1 diabetes is characterized by an absolute insulin deficiency and immune dysregulation. Nearly one in three persons with type 1 diabetes will go on to have diabetic kidney disease, 1 an ...