Background Exercise systolic blood pressure (SBP) indexed to fitness, expressed as SBP divided by peak metabolic equivalents ...

Objective Gene therapies are increasingly being developed and evaluated to treat complex diseases with multiple genetic causes, including cardiovascular diseases (CVDs). However, these studies have ...

Background Discharge N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a recognised prognostic marker after ...

Background Hereditary transthyretin amyloidosis (ATTRv) is a rare multisystem disorder with marked phenotypic heterogeneity.

Objective This study aimed to evaluate the prognostic value of hyperemic microvascular resistance (HMR) and its relationship with hyperemic stenosis resistance (HSR) index and fractional flow reserve ...

Background Heart failure (HF) remains associated with high mortality worldwide despite advances in guideline-directed therapy. Aim To characterise the patterns and causes of death among Thai patients ...

Background To assess implementation of contemporary guideline-directed medical therapy (GDMT) for heart failure (HF) across two nationwide public healthcare systems, including treatment persistence ...

Background and aims Misclassification of heart failure (HF) in primary care electronic health records (EHRs) may affect care quality and outcomes. The OSCAR-HF (Optimising Standards of Care of Heart ...

Objective When advising patients about possible initiation of primary prevention treatment, clinicians currently do not have information on expected impact on lifespan, nor how much this increment ...

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Objective We investigated the benefit of Impella, a modern percutaneous mechanical support (pMCS) device, versus former standard intra-aortic balloon pump (IABP) in acute myocardial infarction ...

Objective The mean closure time of the ductus arteriosus (DA) in full-term neonates is presumed to be 1–2 days after birth; however, whether this rate is accurate throughout the neonatal period is ...