Outcomes of patients with concurrent chronic lymphocytic leukemia and non-small cell lung carcinoma. Circulating tumor DNA as a prognostic biomarker for long-term survival in de-novo oligometastatic ...

In patients with metastatic breast cancer (BC), the prevalence of brain metastases increased with each treatment line, rising the most among patients with hormone receptor (HR)–negative, human ...

Incidence high in HR-negative patients, but there are effective therapies ...

Persons with high-grade gliomas or brain metastases from solid tumors often have a dismal prognosis, despite current approaches such as surgery, radiation, chemotherapy and biological treatments 1,2.

A new study led by researchers at The University of Texas MD Anderson Cancer Center demonstrated that preoperative radiation ...

A team from the Spanish National Cancer Research Centre (CNIO) has discovered a novel way in which tumor cells alter the brain to establish themselves and spread cancer. They also demonstrate that a ...

Brain metastases from colorectal cancer are rare but carry a dismal prognosis. This study aimed to develop and externally validate a prognostic model for individualized survival prediction in affected ...

Brain radiotherapy combined with ICIs improved overall survival and intracranial local control in SCLC patients with brain metastases. WBRT with simultaneous integrated boost (SIB) showed better ...

A new study led by researchers at The University of Texas MD Anderson Cancer Center demonstrated that pre-operative radiation ...

Host Dr. Davide Soldato and guest Dr. Harriet Kluger discuss the JCO article "Phase II Trial of Pembrolizumab in Combination With Bevacizumab for Untreated Melanoma Brain Metastases." Today, Dr.

CNS metastases in EGFR-mutant NSCLC are prevalent and worsen prognosis, especially with acquired progression during treatment. Amivantamab plus lazertinib shows promising CNS activity, but current ...