Membrane proteins are key components of living cells. They constitute one-third of the ORFs of virtually all genomes, perform crucial roles, and are targeted by a huge number of drugs. When present in ...

Type II topoisomerases cleave one DNA duplex (the G, or gate, segment) using two tyrosine residues to attack opposite strands of the phosphodiester backbone. In the process, the enzyme becomes ...

The new QUAFIT method for determining the quaternary structure of biological macromolecular assemblies by analyzing x-ray or neutron small-angle scattering data is presented. The method is based on ...

This is a preview. Log in through your library . Abstract To explore the role of individual residues in the small subunit of ribulose-1,5-bisphosphate carboxylase/oxygenase (EC 4.1.1.39), small ...

This is a preview. Log in through your library . Abstract The Semliki Forest virus (SFV) directs the synthesis of a heterodimeric membrane protein complex which is used for virus membrane assembly ...

The structure of insulin is different among different species of animals. However, essentially it is a protein chain that is similar in many ways among animals. Human insulin is closest in structure ...

The collagen molecule, also known as the “tropocollagen”, is part of larger collagen aggregates such as fibrils. The whole molecule is approximately 300 nm long and 1.5 nm in diameter. Individually ...