Animal preparation. All animal procedures and protocols used in this study were previously reviewed and approved by the Animal Care and Use Committee at the University of Colorado Health Sciences ...

These insights represent the first characterization of risk factors for respiratory failure–related hospitalization among patients with sarcoidosis‐associated pulmonary hypertension (SAPH). Newly ...

VEGF is a potent endothelial cell mitogen with angiogenic and vascular permeability properties (1–3). VEGF is critical to early vascular development inasmuch as gene ablation of a single allele of ...

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A new study published in the American Journal of Pathology suggests that using a vascular homing peptide, which can retain its activity when given sublingually and can selectively target hypertensive ...

The combination of antifibrotic therapy and pulmonary vasodilator therapy improved transplant-free survival but had no significant impact on exercise capacity in pulmonary fibrosis and pulmonary ...

J Gastroenterol Hepatol. 2013;28(2):213-219. The majority of research into the molecular basis of HPS has been performed in rats that have undergone surgical bile duct ligation (BDL). These animals ...

https://doi.org/10.4103/2045-8932.97589 • https://www.jstor.org/stable/10.4103/2045-8932.97589 AbstractPulmonary arterial hypertension (PAH) is a chronic ...

Sept. 23, 2002 — Sildenafil (Viagra) causes preferential pulmonary vasodilation, according to results of an open-label trial published in the Sept. 21 issue of The Lancet. The authors and editorialist ...

The Revised World Health Organization Classification of Pulmonary Hypertension. Pulmonary arterial hypertension is defined as a sustained elevation of pulmonary arterial pressure to more than 25 mm Hg ...

Orphan drug designation from Japan’s Ministry of Health, Labour and Welfare provides key regulatory benefits, including priority review and extended market exclusivity for potential treatments ...

The progressive worsening of liver cirrhosis and portal hypertension (HTN) decreases intra-hepatic nitric oxide (NO), which is counterbalanced by increased NO secretion from adjacent endothelial cells ...