Cryo-EM structure of the Giardia ribosome reveals a highly compact, GC-rich rRNA with eukaryotic r-proteins. (A) Structure of the Giardia ribosome with all the r-proteins colored (SSU, shades of blue ...

Research by UC Santa Cruz molecular biologist Harry Noller and his collaborators has led to the first direct observations of the mechanism for protein synthesis in living cells. Their new findings on ...

Translation factors eIF1A and eIF5B are key repressors of an abnormal protein translation process linked to neurodegenerative ...

It is well known that many biological phenomena require protein synthesis for their manifestation. These include obvious processes such as growth, but also processes within the brain, such as memory.

TrpRS was found to exist in two different forms, allowing it to either add tryptophan to a protein chain or inhibit angiogenesis, as reported in a Nature journal. Scientists from The Scripps Research ...

In all eukaryotic organisms, genetic material is stored in the cell nucleus in the form of DNA. In order to be used, this DNA is first transcribed into messenger RNA in the cell cytoplasm, then ...

A team has recreated the harmful RAN translation process triggered by C9orf72 repeat expansions in ALS and FTD. Using a fully ...

Scientists from Uppsala University have used cryo-electron microscopy to reveal details of the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrhoeal disease. The ...