Abrupt correction of chronic hyponatraemia can cause osmotic demyelination syndrome (ODS) characterized by massive astrocytic death. New research shows that this astrocyte loss is caused by severe ...

Findings reveal that microglia may serve as a potential therapeutic target for the treatment of hyponatremia-related neurological dysfunctions and osmotic demyelination syndrome (ODS) Low serum sodium ...

Sodium correction limits have been around since bed rest for back pain. The latter is gone but the former persists. While bed rest simply delays recovery, rapid sodium correction may cause osmotic ...

If a patient with chronic hyponatremia presents with severe symptoms (e.g. a seizure), the clinician should suspect that an element of acute hyponatremia, and/or an underlying central nervous system ...

Hyponatremia: Is Rapid Correction a Risk or Relief? Rapid sodium correction for hyponatremia could lead to the rare condition osmotic demyelination syndrome. Aaron Holley, MD, shares his thoughts on a ...

The FDA has approved Samsca tablets (tolvaptan) to treat hyponatremia, one of the most common electrolyte disorders seen in hospitalized patients. Hypnoatremia is associated with heart failure, ...