Understanding the best ways to get a membrane protein to its destination in a cell is crucial, and the best method to make this happen is still unclear. Cell-free systems allow for interactions ...
In an effort to reveal the inner workings of a protein that serves as a cell's damage detection system, scientists at Johns ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 5 (February 4, 2020), pp. 2241-2242 (2 pages) D. Krepel, A. Davtyan, N ...
From hemoglobin that carries oxygen, to enzymes and hormones that turn cells on and off, to antibodies that fight infection, proteins seem to do it all. There are many different types of proteins, ...
In an effort to reveal the inner workings of a protein that serves as a cell's damage detection system, scientists at Johns Hopkins and the ...
Evo’s success wasn’t limited to proteins. When they tested a different toxin that had an RNA-based inhibitor, the system ...
Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...
As people around the world marveled in July at the most detailed pictures of the cosmos snapped by the James Webb Space Telescope, biologists got their first glimpses of a different set of images — ...
With this in mind, Bruhn, Saphire, and colleagues subjected the protein to X-ray crystallography, observing diffraction patterns that revealed its shape: “a long, parallel, tetrameric, coiled coil ...
As bispecifics, ADCs, protein degraders, and AI-designed mini-proteins move into the clinic, discovery teams face a new ...
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