10 Theoretically, VEP could be used to measure remyelination ... but following acute optic neuritis 75% of patients typically lose 10–40 µm of RNFL thickness over 3–6 months, 5 and OCT ...

A VEP test can provide evidence of damage or disruption of optic nerve function. MS causes demyelination, but so do other conditions such as optic neuritis and neuromyelitis optica spectrum disorder.

Optic neuritis (ON) is an inflammation that damages your optic nerve. It can cause vision loss and pain when you move your eyes. As the inflammation goes away, your symptoms usually get better.

Optic Neuritis: Clinical Features Optic neuritis refers to inflammation of the optic nerve. The term may be used broadly in reference to many causes of optic nerve inflammation including systemic ...

In this Healio Video Perspective from Hawaiian Eye 2025, Riad Sherif, MD, CEO of Oculis, discusses data on OCS-05 for the ...

The trial met safety and efficacy endpoints. OCS-05 met safety and efficacy endpoints in the treatment of acute optic neuritis in a phase 2 trial, according to a press release from Oculis.

OCS-05 demonstrates safety and efficacy in treating acute optic neuritis, receiving FDA IND clearance for clinical development in the U.S. Small sample size of only 36 patients in the Phase 2 ...