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"Mouse norovirus grew just fine in human cells," Virgin said. "This tells us that the species restriction is due to the ability to get inside the cells in the first place.
The researchers also found that mouse norovirus requires a second molecule, or cofactor, to infect cells; CD300lf by itself isn't enough. But they were unable to nail down the molecule's identity.
Norovirus is the most common viral cause of diarrhea worldwide, but because of an inability to grow it in a lab, scientists still know little about how it infects people and causes disease. Now, ...
The researchers also found that mouse norovirus requires a second molecule, or cofactor, to infect cells; CD300lf by itself isn't enough. But they were unable to nail down the molecule's identity.
image: Mouse norovirus has two capsid structures (type A and type B). Type A particles propagate about 4 hours faster than type B particles (bottom). view more Credit: Kazuyoshi Murata ...
Even in immunized animals, noroviruses can escape the immune system and still spread by hiding out in an extremely rare type of cell in the gut, a new mouse study found.
Norovirus lives in the gut – but mouse studies suggest it may also survive in salivary glands, and the discovery implies there are additional measures we could take to limit infections.
For example, healthy mice infected with a mouse version of norovirus don't develop any symptoms (lucky critters). Then there's the fact that norovirus isn't one virus; it's many.
Across a series of mouse experiments the researchers demonstrated how a norovirus infection can bring on Crohn’s disease. Crohn’s disease is a chronic inflammatory condition that is generally ...
The scientists were hoping to better understand how a norovirus infection may protect a mouse for future infections. As part of their experiment, they reared mice that couldn’t make B cells.
Search location by ZIP code ZIP. Advertisement Medical College Research May Show Link Between Norovirus, Food Allergies ...
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