Metformin is an unassuming hero of modern medicine. For more than 60 years, this humble pill has been a mainstay of diabetes care, helping millions of people manage their blood sugar. It lowers blood ...

This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major ...

The telehealth company Hims & Hers has made waves for its Super Bowl ad that plugged its lower-priced form of injectable semaglutide, the active ingredient in weight loss juggernauts Wegovy and ...

In May 2020, the Food and Drug Administration (FDA) recommended that some makers of metformin extended release remove some of their tablets from the U.S. market. This is because an unacceptable level ...

During a 10-year follow-up, metformin use was associated with significantly lower risks for both dementia and all-cause mortality in patients with overweight or obesity. Metformin, the most widely ...