Assessing the toxicity of food contaminants—including carcinogenic potential—is a major challenge in evaluating the risks ...

Assessing the toxicity of food contaminants—including carcinogenic potential—is a major challenge in evaluating the risks associated with exposure. In ...

Human periportal assembloid, showcasing the three key cell types of the liver: portal fibroblasts (magenta), cholangiocytes (green), and hepatocyte nuclei (blue). All cell borders are delineated in ...

Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

Fats are an important part of the human diet as a major source of energy. Around 90% of the fat stores are on top of muscle, so just under the skin. However, excessive dietary fat intake leads to fat ...

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells, allows us to make the fuel we need from sugars, a ...

Every January, the same wave of "detox" promises rolls in. Juice cleanses, detox teas, charcoal capsules and liver "resets" ...

Chronic liver disease gets worse when the liver's immune system stays overactive, resulting in ongoing inflammation and scarring. Signals from the gut make the situation worse by encouraging immune ...