To determine the extent of LD in the Xq25–q28 region, males of the CEPH, Finnish and Sardinian samples were genotyped with a set of SNP markers. Additional SNP markers were typed in Xq25 (a region of ...

To derive general results, an assumption was made that the populations studied were at quasi-linkage equilibrium (QLE). This assumption follows from Barton's (1995) genome-wide model for studying the ...

Introduction: Families of admixed ancestry are routinely excluded from traditional linkage analysis (LOD score) or are analyzed as deriving from a homogeneous population of the proband's ethnicity.