Insulin under normal circumstances exerts its antiatherogenic action in endothelial cells and VSMCs via the PI 3-kinase signaling pathway. Antiatherogenic aspects of insulin action include stimulation ...

Adding to the growing body of research that proves our microbiome is a powerful ally in fighting disease, scientists have ...

A new study focuses on the insulin receptor to understand its role in the development of type 2 diabetes mellitus, a metabolic disease with a major impact on global health. Insulin resistance precedes ...

An international research team has uncovered a surprising ally in the fight against insulin resistance and type 2 diabetes: a ...

Diabetes now affects about 529 million people worldwide, and roughly 1.6 million die from it each year. At the center of the ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...

Gut-microbe–derived trimethylamine (TMA) blocks a key immune protein, reducing inflammation and improving blood-sugar control.

Researchers have discovered that the microbial metabolite TMA acts as a natural IRAK4 inhibitor, blocking inflammation and ...

Researchers revealed that the microbial metabolite TMA can directly block the immune protein IRAK4, reducing inflammation and ...

A clinical trial found that metformin, a drug typically used for type 2 diabetes, reduced insulin requirements by around 12% ...