An approach that identifies, and predicts compatibility between, chemical and enzyme-sequence spaces can streamline and reduce risk in the discovery of enzymes that can catalyse a desired reaction.

Biological cells invest much of their resources into the production of enzymes, which catalyze the conversion of substrates into products. An international team of bioinformaticians and biophysicists ...

Researchers at the University created an artificial intelligence model named EZSpecificity to test how well certain enzymes and substrates bind to each other. Huimin Zhao and Diwakar Shukla, ...

A single enzyme that can generate all four nucleoside triphosphates, the building blocks of ribonucleic acid (RNA), has been ...

A new microscopy method enables researchers to visualize the activity of the enzymes caspase-3 and alkaline phosphatase in various biological samples (Nat. Methods 2024, DOI: ...

Enzymes are essential for life and are one of the most important types of protein in the human body. Studying enzyme kinetics provides information about the diverse range of reactions in the human ...

Enzymes are biological catalysts that speed up chemical reactions in living organisms. They are essential for life, as they play a crucial role in various biological processes, such as digestion, ...

Cravatt’s strategy for ferreting out new inhibitors for multiple enzymes simultaneously is a good example “of how a strong understanding of enzyme mechanisms can serve as a starting point for studies ...

In the described application - a plug of the substrates was injected into a fused silica capillary column containing the background electrolyte and dissolved enzyme. Using a capillary electrophoresis ...