Congestive heart failure is a disease state distinguished by the regular presence of both renal and hepatic abnormalities in drug handling. One such abnormality involves flaws in the process of drug ...

To test the efficacy of the patch, the team loaded the EW-MNs with rivastigmine (a drug commonly used to treat Alzheimer's and Parkinson's disease). In animal studies using guinea pigs, the ...

A solvent-free mechanochemical grinding technique locks carbamazepine into complexes with larch-derived arabinogalactan and ...

Surface plasmon resonance (SPR) detectors monitor molecular interactions without labels and in real time. SPR imaging (SPRi) has the additional advantage of increased throughput since it monitors ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Vivtex Corporation, a pre-clinical biotechnology company focused on the oral delivery of biologics into systemic blood circulation or localized into GI tissue, ...

Monash University and Seaport Therapeutics have developed a new approach to delivering drug molecules that piggybacks onto natural fat absorption pathways to allow oral delivery of some drugs ...

The demand for novel medications is escalating due to the diminishing efficacy of long-standing antibiotics. Chemists and pharmaceutical researchers are vigorously pursuing innovative compounds, ...

In this interview, News Medical talks to Patrick D. Sinko about the role of particle size, dose, and confinement parameters in advancing drug absorption modeling. Could you explain what a boundary ...

Passive diffusion plays an essential role in oral absorption of drugs through the gastrointestinal tract, penetration across the blood-brain barrier to reach Central Nervous System disease targets, ...

Stone wool fiber dissolution in physiological environments is a key process underlying their long-term behavior and safety, yet robust and reproducible in vitro ...

Though studies evaluating the effects of posture on the absorption of drugs have been conducted, a systematized review revealed critical gaps in methodology. Of 18 original research articles selected ...