Musculoskeletal disorders affect the bones, joints, muscles, and connective tissue. Many musculoskeletal disorders may occur in children, and some types are more common than others. Musculoskeletal ...

Skeletal muscle channelopathies and myotonic disorders constitute a heterogeneous group of neuromuscular conditions caused by mutations that impair the function of ion channels, including sodium and ...

According to the World Health Organization (WHO), over 150 musculoskeletal disorders typically fall within four categories. Treatment for a musculoskeletal disorder may vary, depending on the symptoms ...

Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders, such as craniosynostosis and chondrodysplasia, which severely affect ...

Osteoporosis is a common skeletal disorder characterized by excessive bone loss, leading to increased fragility and an increased risk of fractures. Osteoclasts, the bone-resorbing cells, are widely ...