Aspirin is considered the cornerstone of secondary prevention of coronary artery disease. However, the evidence supporting aspirin was largely generated before the advent of modern pharmacological and ...

One limitation of the published associations up until that time was that the majority of studies were performed in patients receiving percutaneous coronary interventions (PCI) and often in the setting ...

Consent is an important consideration if introducing testing. A patient expert highlighted that people who have had a stroke often have severe cognitive impairment, may have difficulty with their ...

CHICAGO - Among patients with stable cardiovascular disease who have a genetic variation that diminishes the response to the antiplatelet drug clopidogrel, tripling the standard daily dosage of this ...

An analysis of data from previously published studies indicates that use of the antiplatelet drug clopidogrel for patients who have common genetic variants of a certain gene and are undergoing a ...

Clopidogrel is a commonly prescribed medication used to prevent further heart attacks after an initial event. It needs to be activated in the body to be effective. Studies of European populations show ...

Clopidogrel-treated patients who are genetically predisposed to poorly metabolize the antiplatelet drug are at no greater risk of cardiovascular events than those with a normal genotype, according to ...

The authors of this study evaluated the relationship between genetic variants, drug metabolism, and clinical effectiveness of prasugrel. First, they sought to identify genetic variants that might ...

CHICAGO - Among patients with stable cardiovascular disease who have a genetic variation that diminishes the response to the antiplatelet drug clopidogrel, tripling the standard daily dosage of this ...