Background: Osmotic demyelination syndrome (ODS), which embraces central pontine myelinolysis (CPM) and extrapontine myelinosis (EPM), is often underdiagnosed in clinical practice, but can be fatal.

Central pontine myelinolysis is a neurological disorder. It results from damage to the myelin sheath of your brain cells in certain regions — usually the central pontine region — of your brain. The ...

Cyclosporine A (CsA) is frequently used as GVHD prophylaxis in the setting of haematopoietic progenitor cell transplantation (HPCT). Minor to severe CsA-induced neurologic toxicities have been ...

Sodium correction limits have been around since bed rest for back pain. The latter is gone but the former persists. While bed rest simply delays recovery, rapid sodium correction may cause osmotic ...

Central pontine myelinolysis (CPM) is a rare but severe brain and nervous system disorder. CPM destroys myelin, which is a protective substance surrounding the nerves. CPM often develops in response ...