This system takes advantage of natural transport mechanisms within the blood-brain barrier, including caveolae- and γ-secretase-mediated transcytosis, to move nanoparticles across the barrier ...

Bottlebrush Barrier. The glycocalyx layer (purple, left) that coats brain blood vessels consists of numerous glycoproteins, ...

Contributor Content In his years as Director of Surgical Neuro-Oncology at the University of Southern California (USC), Dr. Thomas Chen has witnessed countless innovations in the world of cancer ...

This system takes advantage of natural transport mechanisms within the blood-brain barrier, including caveolae- and γ-secretase-mediated transcytosis, to move nanoparticles across the barrier ...

Researchers reveal that the loss of mucin-type O-glycosylation in the brain endothelial glycocalyx weakens the blood-brain ...

Getting mRNA into the brain could allow scientists to instruct brain cells to produce therapeutic proteins that can help ...

A protein called HER3, which is present on the blood–brain barrier, helps the tumour-invading protein cross from the ...

A new study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children's Hospital Los Angeles, shows ...

In a study with aging mice, Shi discovered significant changes in the sugary coating (glycocalyx) on cells that form the ...

This system takes advantage of natural transport mechanisms within the blood-brain barrier, including caveolae- and γ-secretase-mediated transcytosis, to move nanoparticles across the barrier ...