CONGENITAL defects in bilirubin metabolism are a relatively infrequent cause of jaundice. If neonatal jaundice is excluded, they can be divided into two groups of cases, depending on whether the ...

Case reports of C.I. and C.S. are as follows: C.I., a 27-year-old man, was born in Greece and emigrated to this country as a child. At the age of 4 years, jaundice was detected clinically for the 1st ...

IN mammals the haem groups of haemoglobin are not re-utilized when red cells break down, but are converted to bilirubin (Fig. 1). This pigment is excreted into the bile as a diglucuronide. The reason ...

Bilirubin, the primary breakdown product of hemoproteins, particularly hemoglobin, plays a key role in the diagnosis, prognosis, and monitoring of liver diseases. In acute liver diseases, such as ...

Extract: The development of hepatic uptake, conjugation, and excretion of bilirubin was investigated in newborn and in adult guinea pigs. Excretion of conjugated bilirubin from liver is rate-limiting ...

Severe hyperbilirubinemia is a medical emergency requiring immediate treatment. Common treatment strategies to lower serum bilirubin levels include hydration, cessation of breastfeeding for a short ...

Screening for severe neonatal hyperbilirubinemia is integral to newborn care. Predischarge risk assessment relies on documentation of visual jaundice: age at onset and progression; identification of ...

The strategy includes examination of infant eye color, stool color, and prior laboratory results to assess whether drawing a direct or conjugated bilirubin level is warranted. HealthDay News — In a ...

(A) ABC transporters: The normal functioning of ABCG8/ABCG5, ABCB4, and ABCB11 enables the transport of cholesterol, bile acids, and lipids into bile (left). Mutations in any of these result in ...

Bilirubin is a normal by-product that is formed after the breakdown of old red blood cells. It contains haemoglobin - an oxygen carrying protein in blood. Normally the life span of a red blood cell is ...