Ascending thoracic aortic disease is an important cause of sudden death in the U.S., yet most aortic aneurysms are identified incidentally. To improve assessment of patients who may be at risk for ...

Using human cells in laboratory rats, Michigan Medicine researchers have developed a functional model of thoracic aortic aneurysm, creating opportunities for more effective understanding of disease ...

Using human cells in laboratory rats, Michigan Medicine researchers have developed a functional model of thoracic aortic aneurysm, creating opportunities for more effective understanding of disease ...

The arterial vasculature is the second most frequently calcified structure in the human body after the skeleton. Calcification of the aorta and aortic valves occurs in most individuals in westernized ...

Due to the sudden rupture of the aortic wall, aortic dissection is a life-threatening condition that requires immediate medical attention, as it can lead to vascular collapse. Individuals with ...

BACKGROUND: Aortic valve calcification increases leaflet stiffness and contributes to the development of calcific aortic valve disease. The molecular and cellular mechanisms underlying calcification ...

Although congenital aortic valve disease (AVD) is one of the most prevalent types of congenital heart disease, affecting 1% to 2% of the population, the understanding of the molecular genetics and ...