Cytotoxic agents are substances that destroy cells. “Cytotoxic” means toxic or deadly to cells. In the treatment of cancer, cytotoxic agents are used to prevent cancer cells from dividing and ...

Chemotherapeutic alkylating agents induce a range of cytotoxic and mutagenic adducts onto DNA. Alkylating agent-induced damage to DNA is sensed and repaired by different cellular mechanisms, including ...

There are many different types of cancer medications. These include alkylating agents, antimetabolites, and plant alkaloids. Doctors can use cancer medications either on their own or in combination ...

Evaluating scholastic achievement in pediatric brain tumor survivors compared to healthy controls.

None of the above studies reported increased risk of breast cancer after leukemia, or evaluated the influence of chemotherapy on breast cancer risk in survivors unexposed to chest radiotherapy.

Regulated necrosis has emerged as a major cell death mechanism in response to different forms of physiological and pharmacological stress. The AlkB homolog 7 (ALKBH7) protein is required for regulated ...