A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid without ...

Amide bonds connect the amino acids in proteins and occur in many other useful molecules. An amide-forming reaction that turns the conventional approach on its head offers a practical way of making ...

Research groups led by Qing-Yuan Meng from the Institute of Chemistry, Chinese Academy of Sciences, and Xiu-Long Yang from Hebei University recently reported a novel acylation reaction for ...

A new reaction that uses an atypical starting material to create amide linkages could make it easier to prepare peptides and other amide-containing compounds that have been difficult to make until now ...

DESPITE THEIR FUNDAMENTAL ROLE in chemical and biochemical systems, amides are tough to make. Routes to this functional group usually employ toxic reagents, such as thionyl chloride; require corrosive ...