La Crosse is a city in and the county seat of La Crosse County, Wisconsin, United States. Positioned alongside the Mississippi River, La Crosse is the largest city on Wisconsin's western border. La Crosse's population was 52,680 as of the 2020 census. The city forms the core of the La Crosse–Onalaska metropolitan area, which includes all of La Crosse County and Houston County, Minnesota, with a population of 139,627.
AdFind and Compare Great Deals on Hotels in La Crosse, WI and You Can Save Big! Get the Most Out of Your Trip with Package Deals. Explore Fun Things to Do On Your Stay.