Downtown San Antonio is the central business district of San Antonio, Texas and the urban core of Greater San Antonio, a metropolitan area with nearly 2.5 million people. Downtown San Antonio is encircled by 1604 and I-410 loops and three interstate freeways: I-35, I-37, and I-10. Together, the three highways create a rectangular route around the city's urba…Downtown San Antonio is the central business district of San Antonio, Texas and the urban core of Greater San Antonio, a metropolitan area with nearly 2.5 million people. Downtown San Antonio is encircled by 1604 and I-410 loops and three interstate freeways: I-35, I-37, and I-10. Together, the three highways create a rectangular route around the city's urban core: I-35 to the north and west, I-37 to the east, and I-10 to the south. The rectangular loop has a nine-mile circumference and is known as the "Downtown Loop" or "Central Loop", which encompasses both it and Southtown.