WEBThe primary advantages ascribed to the incorporation of vasoconstrictors in local anesthetic solutions are: an enhancement of local anesthesia, a reduction in peak plasma concentrations of the anesthetic agent, and control of local bleeding.
Local anaesthetics combined with vasoconstrictors in patients with ...
WEBJul 15, 2021 · Cardiovascular effect of dental anesthesia with articaine (40 mg with epinefrine 0,5 mg % and 40 mg with epinefrine 1 mg%) versus mepivacaine (30 mg and 20 mg with epinefrine 1 mg%) in medically compromised cardiac patients: a cross-over, randomized, single blinded study.
Clinical use of local anesthetics in anesthesia - UpToDate
WEBApr 26, 2024 · Local anesthetics (LAs) are used to block transmission of impulses in nerve fibers, to reduce or eliminate sensation. LAs may be used for neuraxial analgesia and anesthesia, peripheral nerve blocks, subcutaneous …
Use of vasoconstrictors in anesthesia - PubMed
WEBThe use of vasoconstrictor agents in combination with local anesthetic solutions is discussed, including their pharmacology, dosage, side effects, and contraindications to their use. Also noted are important anesthetic drug interactions with vasoconstrictor agents as they are used in combination with local anesthesia and general anesthetic agents.
Norepinephrine - StatPearls - NCBI Bookshelf
WEBMay 8, 2023 · Norepinephrine's predominant use is as a peripheral vasoconstrictor. Specifically, the FDA has approved its use for blood pressure control in specific acute hypotensive states and is a potential adjunct in the treatment of …
Effects of Local Anesthetics With Vasoconstrictors on Dental Pulp …
WEBDec 15, 2021 · The injection of local anesthetic solutions containing vasoconstrictors (LE or PF) transiently caused significant decreases in PBF that resulted in significant decreases in P pulp O 2. The recovery of P pulp O 2 was faster than PBF regardless of the vasoconstrictor used.
Basic pharmacology of local anaesthetics - BJA Education
WEBJul 17, 2019 · Local anaesthetic agents suppress action potentials in excitable tissues by blocking voltage-gated Na+ channels. In doing so, they inhibit action potentials in nociceptive fibres and so block the transmission of pain impulses.
Local Anesthesia in Dentistry - Wiley Online Library
WEBJan 12, 2024 · The characteristics of epinephrine, norepinephrine, and levonordefrin are reviewed, and we consider the advantages and indications, clinical efficacy, tolerance, and adverse effects of phentolamine.
Overview of Local Anesthesia - SpringerLink
WEBDec 18, 2020 · Vasoactive agents (i.e., vasoconstrictors) are used in conjunction with most local anesthetic agents to combat their inherent vasodilatory action. The most commonly used local anesthetic agents include lidocaine, …
Pharmacology of Local Anesthetics | SpringerLink
WEBOct 20, 2022 · Local anesthetics are sodium channel blockers which can be used to prevent depolarization of nerve tissue, producing sensory and motor blockade. Factors that influence the onset time and density of nerve blockade include the …
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